Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.82 |
| ▸ | ATM | Q13315 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.49 |
| ▸ | ACACA | Q13085 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388984 | 1.00 | KMT2A (0.82) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL388983 | 1.00 | KMT2A (0.82) | KMT2AATMMEN1MAPK1LMNA | |
| Dimethylamine SCHEMBL10425391 | 0.98 | KMT2A (0.79) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16604417 | 0.92 | KMT2A (0.70) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL25964562 | 0.92 | KMT2A (0.70) | KMT2AATMMEN1MAPK1LMNA | |
| Aminobenzoic Acid SCHEMBL7274588 | 0.91 | KMT2A (0.70) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16604445 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16609114 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL7275174 | 0.91 | KMT2A (0.72) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL17961971 | 0.91 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745192-A | Substituted phenylalanine derivatives | 拜耳制药股份公司 | 2016-07-06 | — | — | CN | disclosed |