Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16604598 | 0.87 | ESR1 (0.42) | PTGER4GRIA1CACNG8CACNG2SIRT2 | |
| SCHEMBL16604639 | 0.83 | PDE10A (0.37) | PTGER4PDE10ARXFP1HDAC1HDAC8 | |
| SCHEMBL16604637 | 0.83 | ESR1 (0.39) | PTGER4GRIA1CACNG8CACNG2SIRT2 | |
| SCHEMBL16604629 | 0.81 | ESR1 (0.41) | PTGER4GRIA1CACNG8CACNG2SIRT2 | |
| SCHEMBL15976940 | 0.81 | — | — | |
| SCHEMBL16604636 | 0.80 | ESR1 (0.46) | PTGER4GRIA1CACNG8CACNG2PDE10A | |
| SCHEMBL15706166 | 0.79 | NR3C1 (0.31) | — | |
| SCHEMBL16604577 | 0.79 | GRIA1 (0.56) | GRIA1CACNG8CACNG2RXFP1HDAC1 | |
| SCHEMBL15706196 | 0.79 | NR3C1 (0.31) | — | |
| SCHEMBL12912474 | 0.79 | GRIA1 (0.46) | PTGER4GRIA1CACNG8CACNG2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9461261-B2 | Organic compounds and organic light-emitting devices including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-10-04 | — | — | US | disclosed |
| US-9461261-B2 | Organic compounds and organic light-emitting devices including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-10-04 | — | — | US | disclosed |
| US-20150090963-A1 | ORGANIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-04-02 | — | — | US | disclosed |
| US-20150090963-A1 | ORGANIC COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-04-02 | — | — | US | disclosed |