Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045753 | 1.00 | KMT2A (0.34) | KMT2ACRBNCA1CA2CA4 | |
| SCHEMBL2044931 | 1.00 | KMT2A (0.34) | KMT2ACRBNCA1CA2CA4 | |
| SCHEMBL1660612 | 1.00 | KMT2A (0.34) | KMT2ACRBNCA1CA2CA4 | |
| SCHEMBL1659708 | 1.00 | KMT2A (0.34) | KMT2ACRBNCA1CA2CA4 | |
| SCHEMBL1660756 | 1.00 | KMT2A (0.34) | KMT2ACRBNCA1CA2CA4 | |
| SCHEMBL727453 | 1.00 | KMT2A (0.34) | KMT2ACRBNCA1CA2CA4 | |
| SCHEMBL2044674 | 1.00 | KMT2A (0.34) | KMT2ACRBNCA1CA2CA4 | |
| SCHEMBL2044296 | 1.00 | KMT2A (0.34) | KMT2ACRBNCA1CA2CA4 | |
| SCHEMBL2051736 | 0.86 | ALDH1A1 (0.31) | — | |
| SCHEMBL2047253 | 0.86 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173846-B2 | Substituted cyclohexenones | FIRMENICH SA (CH) | 2012-05-08 | — | — | US | claimed |
| EP-2247564-B1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH & CIE (CH) | 2011-06-29 | — | — | EP | claimed |
| JP-2011510973-A | — | — | 2011-04-07 | — | — | JP | claimed |
| EP-2247564-A1 | SUBSTITUTED CYCLOHEXENONES | Firmenich S.A. (CH) | 2010-11-10 | — | — | EP | claimed |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2010-10-28 | — | — | US | claimed |
| WO-2009095804-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2009-08-06 | — | — | WO | claimed |
| EP-1718591-B1 | A PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CYCLOHEXENONES | FIRMENICH & CIE (CH) | 2008-10-15 | — | — | EP | claimed |
| US-7332633-B2 | Process for the preparation of optically active cyclohexenones | FIRMENICH SA (CH) | 2008-02-19 | — | — | US | claimed |
| US-20060252967-A1 | Process for the preparation of optically active cyclohexenones | FIRMENICH SA (CH) | 2006-11-09 | — | — | US | claimed |
| US-8173846-B2 | Substituted cyclohexenones | FIRMENICH SA (CH) | 2012-05-08 | — | — | US | disclosed |
| EP-2247564-B1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH & CIE (CH) | 2011-06-29 | — | — | EP | disclosed |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2010-10-28 | — | — | US | disclosed |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2010-10-28 | — | — | US | disclosed |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2010-10-28 | — | — | US | disclosed |
| EP-1910261-B1 | SUBSTITUTED CYCLOHEXANONES | FIRMENICH & CIE (CH) | 2009-11-11 | — | — | EP | disclosed |
| US-7470820-B2 | Substituted cyclohexanones | FIRMENICH SA (CH) | 2008-12-30 | — | — | US | disclosed |
| EP-1718591-B1 | A PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE CYCLOHEXENONES | FIRMENICH & CIE (CH) | 2008-10-15 | — | — | EP | disclosed |
| US-20080228008-A1 | Substituted Cyclohexanones | FIRMENICH SA (CH) | 2008-09-18 | — | — | US | disclosed |
| US-7332633-B2 | Process for the preparation of optically active cyclohexenones | FIRMENICH SA (CH) | 2008-02-19 | — | — | US | disclosed |
| US-20060252967-A1 | Process for the preparation of optically active cyclohexenones | FIRMENICH SA (CH) | 2006-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | OXER1, ORC3, OR10J3 | KMT2A 4285/4885CRBN 1954/4885CA1 1603/4885 |
| US-20080228008-A1 | Substituted Cyclohexanones | NQO1, CYP2J2, CBR3 | KMT2A 3910/4885CRBN 2445/4885CA1 3946/4885 |
| US-20060252967-A1 | Process for the preparation of optically active cyclohexenones | KCNJ11, KCNJ1, KCNK17 | KMT2A 3017/4885CRBN 2445/4885CA1 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.