Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18011638 | 1.00 | KMT2A (0.63) | KMT2AATMMEN1MAPK1ACACB | |
| SCHEMBL16606803 | 0.92 | KMT2A (0.53) | KMT2AATMMEN1MAPK1ACACB | |
| SCHEMBL18011627 | 0.92 | KMT2A (0.53) | KMT2AATMMEN1MAPK1ACACB | |
| SCHEMBL18062586 | 0.89 | KMT2A (0.61) | KMT2AATMMEN1MAPK1ACACB | |
| SCHEMBL16604454 | 0.89 | KMT2A (0.61) | KMT2AATMMEN1MAPK1ACACB | |
| SCHEMBL17961971 | 0.89 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16604349 | 0.89 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16604445 | 0.89 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL18093140 | 0.89 | KMT2A (0.69) | KMT2AATMMEN1MAPK1LMNA | |
| SCHEMBL16604417 | 0.88 | KMT2A (0.70) | KMT2AATMMEN1MAPK1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044167-A1 | SUBSTITUTED PHENYLALANINE DERIVATIVES AS MODULATORS OF FACTOR XIA | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-02 | — | — | WO | disclosed |