Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.71 |
| ▸ | BACE1 | P56817 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.67 |
| ▸ | IGF1R | P08069 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | DRD1 | P21728 | 3/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | DRD5 | P21918 | 3/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107956 | 0.85 | ALOX15 (0.80) | MAPTKDM4EALDH1A1GAAALOX5 | |
| SCHEMBL30631592 | 0.85 | ALOX15 (0.80) | MAPTKDM4EALDH1A1GAAALOX5 | |
| Hydroxytyrosol SCHEMBL29414541 | 0.83 | MAPT (1.00) | MAPTKDM4EALDH1A1GAAALOX5 | |
| Hydroxytyrosol SCHEMBL44363 | 0.83 | MAPT (1.00) | MAPTKDM4EALDH1A1GAAALOX5 | |
| SCHEMBL8431254 | 0.82 | ALOX15 (0.76) | MAPTKDM4EALDH1A1GAAALOX5 | |
| SCHEMBL2307446 | 0.80 | ALOX15 (1.00) | MAPTKDM4EALDH1A1GAAALOX5 | |
| SCHEMBL107170 | 0.80 | ALOX15 (0.90) | MAPTKDM4EALDH1A1GAAALOX5 | |
| SCHEMBL31556189 | 0.78 | ALOX15 (0.95) | MAPTKDM4EALDH1A1GAAALOX5 | |
| SCHEMBL15387372 | 0.78 | CA1 (0.85) | MAPTKDM4EALDH1A1GAAALOX5 | |
| SCHEMBL31556198 | 0.78 | ALOX15 (0.95) | MAPTKDM4EALDH1A1GAAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044470-A1 | NOVEL ANTI-INFLAMMATORY AGENTS BASED ON POLYPHENOLS OF THE OLIVE TREE | UNVIERSIDAD DE SEVILLA (ES) | 2015-04-02 | — | — | WO | disclosed |