Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | GLI1 | P08151 | 1/20 | 0.45 |
| ▸ | GLI2 | P10070 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17204643 | 1.00 | NAAA (0.54) | NAAAPOLBCNR1CNR2HIF1A | |
| Hydrochloric Acid SCHEMBL17203996 | 0.99 | NAAA (0.52) | NAAAPOLBCNR1CNR2HIF1A | |
| Hydrochloric Acid SCHEMBL17204549 | 0.99 | NAAA (0.52) | NAAAPOLBCNR1CNR2HIF1A | |
| SCHEMBL8974580 | 0.89 | POLB (0.65) | NAAAPOLBCNR1KDM4A | |
| SCHEMBL28414032 | 0.89 | POLB (0.65) | NAAAPOLBCNR1KDM4A | |
| SCHEMBL6923899 | 0.87 | CNR1 (0.69) | POLBCNR1CNR2SOAT1TACR1 | |
| SCHEMBL13883466 | 0.87 | GLI1 (0.58) | NAAAPOLBCNR1CNR2GLI1 | |
| SCHEMBL9542025 | 0.87 | GLI1 (0.58) | NAAAPOLBCNR1CNR2GLI1 | |
| SCHEMBL16609241 | 0.84 | POLB (0.52) | POLBCNR1CNR2HIF1ASOAT1 | |
| SCHEMBL17519900 | 0.84 | GLI1 (0.59) | POLBCNR1CNR2ESRRGGLI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016877-B | Acetylaniline compounds and application thereof in preparation of mirabegron | 南京海融制药有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-104016877-A | Acetylaniline compounds and application thereof in preparation of mirabegron | NANJING HAIRONG PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-09-03 | — | — | CN | claimed |
| CN-111269157-B | Amisulpride impurity and preparation method thereof | 南京海纳医药科技股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-111269157-A | Amisulpride impurity and preparation method thereof | 南京海纳医药科技股份有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-104016877-B | Acetylaniline compounds and application thereof in preparation of mirabegron | 南京海融制药有限公司 | 2017-02-15 | — | — | CN | disclosed |
| WO-2016024284-A2 | A PROCESS FOR THE PREPARATION OF MIRABEGRON AND ITS INTERMEDIATES | WANBURY LTD. (IN) | 2016-02-18 | — | — | WO | disclosed |
| WO-2016024284-A2 | A PROCESS FOR THE PREPARATION OF MIRABEGRON AND ITS INTERMEDIATES | WANBURY LTD. (IN) | 2016-02-18 | — | — | WO | disclosed |
| WO-2015162536-A1 | NOVEL PROCESS FOR PREPARATION OF MIRABEGRON AND IT'S INTERMEDIATE | CALYX CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162536-A1 | NOVEL PROCESS FOR PREPARATION OF MIRABEGRON AND IT'S INTERMEDIATE | CALYX CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015044965-A1 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-04-02 | — | — | WO | disclosed |
| CN-104016877-A | Acetylaniline compounds and application thereof in preparation of mirabegron | NANJING HAIRONG PHARMACEUTICAL TECHNOLOGY CO LTD | 2014-09-03 | — | — | CN | disclosed |