SCHEMBL16610042

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16610043	0.81	MAPT (0.55)	KMT2AMEN1TDP1L3MBTL1MAPT
	SCHEMBL16599246	0.81	KMT2A (0.38)	KMT2AMEN1TDP1CYP3A4L3MBTL1
	SCHEMBL23639738	0.79	KMT2A (0.72)	KMT2AMEN1TDP1CYP3A4L3MBTL1
	SCHEMBL31321630	0.79	KMT2A (0.72)	KMT2AMEN1TDP1CYP3A4L3MBTL1
	SCHEMBL16599389	0.79	TSHR (0.50)	KMT2AMEN1TDP1L3MBTL1HPGD
	SCHEMBL16610045	0.78	KMT2A (0.71)	KMT2AMEN1TDP1CYP3A4L3MBTL1
	SCHEMBL8128802	0.78	KDM4E (0.44)	KMT2AMEN1HPGDMAPTLMNA
	SCHEMBL6475832	0.77	KMT2A (0.46)	KMT2ATDP1CYP3A4HPGDPOLB
	SCHEMBL2950986	0.77	EGFR (0.47)	CYP3A4MAPTADRB1ADRB3KDM4E
	SCHEMBL9340141	0.77	KMT2A (0.69)	KMT2AMEN1TDP1CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.