Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 16/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597526 | 0.92 | CHRM1 (0.54) | CHRM1USP30CHRM5 | |
| SCHEMBL17924348 | 0.90 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL16610091 | 0.89 | CNR1 (0.49) | CHRM1USP30 | |
| SCHEMBL16597412 | 0.86 | CHRM1 (0.56) | CHRM1USP30CHRM5 | |
| SCHEMBL16610132 | 0.86 | CHRM1 (0.67) | CHRM1 | |
| SCHEMBL17929750 | 0.84 | CHRM1 (0.71) | CHRM1 | |
| SCHEMBL16597405 | 0.82 | CHRM1 (0.52) | CHRM1USP30 | |
| SCHEMBL16597400 | 0.81 | CHRM1 (0.49) | CHRM1USP30 | |
| SCHEMBL16597442 | 0.80 | CHRM1 (0.48) | CHRM1USP30 | |
| SCHEMBL17924278 | 0.80 | CHRM1 (0.65) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044072-A1 | INDOL AND INDAZOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-04-02 | — | — | WO | disclosed |