Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.49 |
| ▸ | CNR2 | P34972 | 8/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597400 | 0.92 | CHRM1 (0.49) | CHRM1USP30 | |
| SCHEMBL16597442 | 0.90 | CHRM1 (0.48) | CNR1CNR2CHRM1USP30 | |
| SCHEMBL17924373 | 0.89 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL16610090 | 0.89 | CHRM1 (0.54) | CHRM1USP30 | |
| SCHEMBL16597530 | 0.85 | CHRM1 (0.51) | CHRM1USP30 | |
| SCHEMBL16610400 | 0.85 | CHRM1 (0.52) | CNR1CNR2CHRM1AURKAAURKB | |
| SCHEMBL21362263 | 0.84 | CHRM1 (0.60) | CNR1CNR2CHRM1 | |
| SCHEMBL16597380 | 0.83 | CHRM1 (0.49) | CHRM1USP30 | |
| SCHEMBL16597584 | 0.83 | CHRM1 (0.64) | CHRM1AURKAAURKB | |
| SCHEMBL16597382 | 0.81 | CHRM1 (0.47) | CNR1CNR2CHRM1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044072-A1 | INDOL AND INDAZOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-04-02 | — | — | WO | disclosed |