Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 5/20 | 0.43 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610404 | 0.86 | TRPV1 (0.49) | TRPV1ACHEHPGDALDH1A1SLC5A1 | |
| SCHEMBL28663853 | 0.84 | TRPV1 (0.57) | TRPV1ACHEALDH1A1KDM4ECYP1A2 | |
| SCHEMBL16610410 | 0.84 | TRPV1 (0.57) | TRPV1ACHEALDH1A1KDM4ECYP1A2 | |
| SCHEMBL16610373 | 0.83 | KDM4E (0.52) | HPGDALDH1A1LMNASLC5A1SLC5A2 | |
| SCHEMBL16610335 | 0.83 | TRPV1 (0.47) | TRPV1ACHEHPGDALDH1A1LMNA | |
| SCHEMBL16610336 | 0.79 | TRPV1 (0.52) | TRPV1ACHEHPGDALDH1A1KDM4E | |
| SCHEMBL28012614 | 0.79 | TRPV1 (0.52) | TRPV1ACHEHPGDALDH1A1KDM4E | |
| SCHEMBL16610376 | 0.76 | APP (0.56) | TRPV1ACHEHPGDALDH1A1KDM4E | |
| SCHEMBL28012613 | 0.75 | TRPV1 (0.60) | TRPV1ACHEHPGDALDH1A1HTT | |
| SCHEMBL16610369 | 0.75 | TRPV1 (0.60) | TRPV1ACHEHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015043522-A1 | TRIFLUOROMETHYL-CONTAINING AMIDE ALKALOID, MANUFACTURING METHOD AND PHARMACEUTICAL USE THEREOF | 天士力制药集团股份有限公司 | 2015-04-02 | — | — | WO | disclosed |