Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL42945 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29587574 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21555662 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL66313 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668547 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1458270 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL8845344 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109046412-B | Catalyst for preparing maleic anhydride by oxidizing n-butane and preparation method thereof | 常州新日催化剂股份有限公司 | 2021-05-25 | — | — | CN | claimed |
| WO-2024089306-A1 | GAS-SOLID CATALYTIC PROCESS FOR CONVERTING AN OLEFIN INTO ALCOHOL | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2024-05-02 | — | — | WO | disclosed |
| US-11318214-B2 | Iron oxide mesoporous microparticle drug carrier | NATIONAL GUARD HEALTH AFFAIRS (SA) | 2022-05-03 | — | — | US | disclosed |
| US-20210393798-A1 | IRON OXIDE MESOPOROUS MICROPARTICLE DRUG CARRIER | NATIONAL GUARD HEALTH AFFAIRS (SA) | 2021-12-23 | — | — | US | disclosed |
| CN-109046412-B | Catalyst for preparing maleic anhydride by oxidizing n-butane and preparation method thereof | 常州新日催化剂股份有限公司 | 2021-05-25 | — | — | CN | disclosed |
| US-9808791-B2 | Visible-light photocatalyst particles and method for manufacturing same | TOTO LTD. (JP) | 2017-11-07 | — | — | US | disclosed |
| US-20160137496-A1 | VISIBLE LIGHT RESPONSIVE PHOTOCATALYST MATERIAL | TOTO LTD. (JP) | 2016-05-19 | — | — | US | disclosed |
| EP-3012022-A1 | VISIBLE LIGHT RESPONSIVE PHOTOCATALYST MATERIAL | Toto Ltd. (JP) | 2016-04-27 | — | — | EP | disclosed |
| US-20150251172-A1 | COMPOSITE PHOTOCATALYST, AND PHOTOCATALYST MATERIAL | TOTO LTD. (JP) | 2015-09-10 | — | — | US | disclosed |
| EP-2898951-A1 | COMPOSITE PHOTOCATALYST, AND PHOTOCATALYST MATERIAL | Toto Ltd. (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-20150107984-A1 | VISIBLE-LIGHT PHOTOCATALYST PARTICLES AND METHOD FOR MANUFACTURING SAME | TOTO LTD. (JP) | 2015-04-23 | — | — | US | disclosed |
| EP-2857097-A1 | VISIBLE-LIGHT PHOTOCATALYST PARTICLES AND METHOD FOR MANUFACTURING SAME | Toto Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |