SCHEMBL16611196

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16610948	0.83	PIK3CD (0.40)	CMKLR1PIK3CDABL1EGFRHCK
	SCHEMBL16611356	0.83	JAK2 (0.49)	PIK3CDABL1EGFRHCKSRC
	SCHEMBL16611757	0.83	JAK2 (0.47)	PIK3CDABL1EGFRHCKSRC
	SCHEMBL16610875	0.82	JAK2 (0.52)	PIK3CDABL1EGFRHCKSRC
	SCHEMBL16610922	0.81	JAK2 (0.52)	PIK3CDABL1EGFRHCKSRC
	SCHEMBL16611267	0.81	CMKLR1 (0.42)	CMKLR1PIK3CDABL1EGFRHCK
	SCHEMBL18052598	0.81	PIK3CD (0.41)	PIK3CDABL1EGFRHCKSRC
	SCHEMBL16610662	0.81	JAK1 (0.47)	EGFRJAK2JAK1
	SCHEMBL16611535	0.81	JAK2 (0.52)	CMKLR1PRKDCJAK2JAK1
	SCHEMBL16610887	0.80	JAK2 (0.42)	PIK3CDABL1EGFRHCKSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.