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CMKLR1

Chemerin-like receptor 1 · Q99788 · CMKLR1 on Sugi Atlas →

5,971 patent compounds predicted against CMKLR1, 3,127 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4230947 SCHEMBL4230947 0.58 20/20
SCHEMBL4030592 SCHEMBL4030592 0.42 11/20
SCHEMBL4027946 SCHEMBL4027946 0.39 11/20
SCHEMBL1003561 SCHEMBL1003561 0.46 10/20
SCHEMBL4027942 SCHEMBL4027942 0.40 10/20
SCHEMBL4031653 SCHEMBL4031653 0.45 9/20
SCHEMBL4028868 SCHEMBL4028868 0.42 9/20
Lithium Ion Lithium Ion (SCHEMBL1003559) 0.39 9/20
SCHEMBL2830191 SCHEMBL2830191 0.58 8/20
SCHEMBL4025919 SCHEMBL4025919 0.40 8/20
SCHEMBL1005419 SCHEMBL1005419 0.41 7/20
SCHEMBL4030596 SCHEMBL4030596 0.41 7/20
SCHEMBL4025902 SCHEMBL4025902 0.39 7/20
SCHEMBL4026974 SCHEMBL4026974 0.46 6/20
SCHEMBL4026643 SCHEMBL4026643 0.42 6/20
SCHEMBL4026813 SCHEMBL4026813 0.41 6/20
SCHEMBL4031236 SCHEMBL4031236 0.40 6/20
SCHEMBL4028054 SCHEMBL4028054 0.41 5/20
SCHEMBL4031427 SCHEMBL4031427 0.41 5/20
SCHEMBL4027938 SCHEMBL4027938 0.39 5/20

Clinical trials — most relevant to CMKLR1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Renoprotection by Pentoxifylline and Angiotensin Receptor Blocker in Chronic Kidney Disease (CKD) PHASE4UNKNOWN
Biomarker Study of PDR001 in Combination With MCS110 in Gastric Cancer PHASE2UNKNOWN
Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis PHASE2COMPLETED
Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients PHASE2COMPLETED
Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients PHASE1/PHASE2COMPLETED
Anakinra as a Rescue Treatment for Allergic Inflammation PHASE1/PHASE2WITHDRAWN
NIH CCR2 AAA Study EARLY_PHASE1COMPLETED
Circular RNA and Chemerin in Breast Cancer Patient nanUNKNOWN
Chemerin, Fetuin-A, IL-34 and IL-13 Levels in Diabetic Periodontitis Patients nanCOMPLETED
Association of Circulating Chemerin Levels and Arterial Stiffness nanUNKNOWN
Cytokine Expression During Radiation for Breast Cancer nanCOMPLETED
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk nanCOMPLETED
Ankylosing Spondylitis nanNOT_YET_RECRUITING
Apelin12 in Acne Vulgaris nanUNKNOWN
Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly nanRECRUITING
Meteorin-like Levels in Individuals With Periodontitis nanCOMPLETED
The Role of Visfatin in Obesity and Periodontal Disease nanCOMPLETED
The Effects of Sleeve Gastrectomy on Fractalkine nanCOMPLETED
Chemerin and IL-6 Levels in Diabetes and Periodontitis nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
The Role of Neutrophil CD64 and Soluble Triggering Receptor Expressed on Myeloid Cells 1 in Neonatal Sepsis nanUNKNOWN
Genetic Polymorphism Associated With Coronary Heart Disease Susceptibility and Variability of Clopidogrel Response nanACTIVE_NOT_RECRUITING
The Relationship Between Serum Chemokine Ligand 21 (CCL-21) Level and Disease Activity nanNOT_YET_RECRUITING
Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry Bad Cholesterol in the Blood nanCOMPLETED
C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia nanUNKNOWN
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
Relationship Between Maternal Soluble Trigger Receptor Expressed on Myeloid Cells-1 (sTREM-1) and Placenta Accreta Spectrum nanUNKNOWN
Role of the Inflammatory Receptors in the Pathogenesis of Atherosclerosis nanUNKNOWN
Value of Various Chemokines in the Detection and Follow up of RCC nanUNKNOWN
Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a CMKLR1 binder may also engage these)

ProteinNameSimilarity
B1PHQ8 — 1.000 B1PHQ8 →
O35786 — 1.000 O35786 →
B9VR26 — 0.997 B9VR26 →
P97468 — 0.994 P97468 →
P0C7U4 — 0.989 P0C7U4 →
P0C7U5 — 0.988 P0C7U5 →
P30993 — 0.987 P30993 →
P79240 — 0.985 P79240 →
P79175 — 0.985 P79175 →
C5AR1 C5a anaphylatoxin chemotactic receptor 1 0.985 landscape →
P97520 — 0.983 P97520 →
Q2WED0 — 0.983 Q2WED0 →
P79190 — 0.982 P79190 →
P79236 — 0.982 P79236 →
P30992 — 0.982 P30992 →
Q49SQ3 — 0.981 Q49SQ3 →
Q49SQ2 — 0.981 Q49SQ2 →
O70129 — 0.981 O70129 →
P79242 — 0.981 P79242 →
FPR2 N-formyl peptide receptor 2 0.981 landscape →
Q9TUE1 — 0.980 Q9TUE1 →
Q49SQ1 — 0.980 Q49SQ1 →
P79235 — 0.979 P79235 →
P79234 — 0.978 P79234 →
P79177 — 0.977 P79177 →
P79188 — 0.977 P79188 →
P33766 — 0.976 P33766 →
CXCR2 C-X-C chemokine receptor type 2 0.976 landscape →
P55920 — 0.976 P55920 →
O88536 — 0.976 O88536 →