SCHEMBL16612282

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16612179	0.88	POLB (0.45)	POLBPTGS2PDE10APDE2AGRIN1
	SCHEMBL16803699	0.86	AKT1 (0.43)	PDE10AGRIN1GRIN2BKDM4EALDH1A1
	SCHEMBL16612157	0.85	POLB (0.45)	POLBPTGS2ALDH1A1PTGS1PKM
	SCHEMBL15412012	0.85	POLB (0.46)	POLBPTGS2PDE2AKDM4EALDH1A1
	SCHEMBL16613191	0.84	POLB (0.45)	POLBPTGS2GRIN1GRIN2BKDM4E
	SCHEMBL16612238	0.84	POLB (0.47)	POLBPTGS2GRIN1GRIN2BKDM4E
	SCHEMBL29431647	0.83	POLB (0.45)	POLBPTGS2PDE10APDE2AGRIN1
	SCHEMBL14677002	0.83	POLB (0.45)	POLBPTGS2PDE10APDE2AGRIN1
	SCHEMBL20442298	0.83	POLB (0.41)	POLBPTGS2PDE10AGRIN1GRIN2B
	SCHEMBL15411977	0.82	POLB (0.43)	POLBPTGS2PDE10APDE2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.