Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612747 | 1.00 | HCAR2 (0.32) | HCAR2KDM4EATMALDH1A1SLC1A3 | |
| SCHEMBL10967248 | 0.73 | SLC1A3 (0.33) | HCAR2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10967253 | 0.73 | SLC1A3 (0.33) | HCAR2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2890685 | 0.72 | NPSR1 (0.48) | HCAR2KDM4EATMALDH1A1 | |
| SCHEMBL9189705 | 0.72 | NPSR1 (0.48) | HCAR2KDM4EATMALDH1A1 | |
| SCHEMBL2890687 | 0.72 | NPSR1 (0.48) | HCAR2KDM4EATMALDH1A1 | |
| SCHEMBL5514558 | 0.70 | — | — | |
| SCHEMBL4826203 | 0.70 | — | — | |
| SCHEMBL12215996 | 0.70 | — | — | |
| SCHEMBL27514356 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |