Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885322 | 0.89 | MAPK1 (0.64) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL899494 | 0.87 | MAPK1 (1.00) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL29367556 | 0.87 | MAPK1 (1.00) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL29469602 | 0.84 | MAPK1 (0.71) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL31290606 | 0.84 | MAPK1 (0.71) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL30298314 | 0.83 | MAPK1 (0.75) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL31177143 | 0.82 | ALOX15 (1.00) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL29398700 | 0.82 | ALOX15 (1.00) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL30298315 | 0.82 | MEN1 (1.00) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 | |
| SCHEMBL30298317 | 0.82 | MEN1 (1.00) | MAPK1ALDH1A1TDP1L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491899-B1 | DENTIFRICES CONTAINING A RETINOL, PANTHENOL AND BACTERICIDES USED AS PROPHYLACTIC AGENTS FOR ORAL DISEASES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-12-10 | — | — | US | claimed |
| EP-0220890-B1 | ORAL HYGIENE COMPOSITION | BEECHAM GROUP PLC (GB) | 1991-09-11 | — | — | EP | claimed |
| EP-2158894-B1 | Oral cleansing agent | HENKEL AG & CO KGAA (DE) | 2018-11-07 | — | — | EP | disclosed |
| EP-2140853-B1 | Coated particle for use in cosmetics | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2617466-B1 | Colour-stable mouthwash and mouthwash concentrates | HENKEL AG & CO KGAA (DE) | 2016-11-23 | — | — | EP | disclosed |
| US-9446267-B2 | Products comprising a flavoring agent composition | SYMRISE AG (DE) | 2016-09-20 | — | — | US | disclosed |
| EP-1935397-B1 | Oral and tooth care and cleaning agents for combating halitosis | HENKEL AG & CO KGAA (DE) | 2016-03-02 | — | — | EP | disclosed |
| EP-2186506-B1 | Teeth cleaning compound containing menthol with reduced bitter sensation | SYMRISE AG (DE) | 2015-09-30 | — | — | EP | disclosed |
| EP-2025319-B1 | Numbing oral and tooth care and cleaning agents | HENKEL AG & CO KGAA (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-1774954-B1 | Mouthwash and dentifrice and cleansing composition | HENKEL AG & CO KGAA (DE) | 2014-08-13 | — | — | EP | disclosed |
| EP-1806126-B1 | Dental preparations comprising enzymes | HENKEL AG & CO KGAA (DE) | 2014-06-04 | — | — | EP | disclosed |
| WO-2004080434-A1 | ORAL AND DENTAL CARE AGENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-09-23 | — | — | WO | disclosed |
| WO-2004026295-A9 | USE OF SKIN-PROTECTING SUBSTANCES | PHENION GMBH & CO KG (DE) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004026295-A2 | USE OF SKIN-PROTECTING SUBSTANCES | PHENION GMBH & CO. KG (DE) | 2004-04-01 | — | — | WO | disclosed |
| WO-2004026856-A1 | TOCOPHERYL ESTER | PHENION GMBH & CO. KG (DE) | 2004-04-01 | — | — | WO | disclosed |
| US-6491899-B1 | DENTIFRICES CONTAINING A RETINOL, PANTHENOL AND BACTERICIDES USED AS PROPHYLACTIC AGENTS FOR ORAL DISEASES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1098629-B1 | ANTI-INFLAMMATORY DENTAL CARE AGENTS | HENKEL KGAA (DE) | 2002-09-25 | — | — | EP | disclosed |
| EP-1098629-A1 | ANTI-INFLAMMATORY DENTAL CARE AGENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000006109-A1 | ANTI-INFLAMMATORY DENTAL CARE AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-02-10 | — | — | WO | disclosed |
| EP-0220890-B1 | ORAL HYGIENE COMPOSITION | BEECHAM GROUP PLC (GB) | 1991-09-11 | — | — | EP | disclosed |