Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 18/20 | 0.51 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.51 |
| ▸ | KYAT3 | Q6YP21 | 2/20 | 0.51 |
| ▸ | GOT1 | P17174 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786050 | 0.90 | AADAT (0.48) | AADATKYAT1KYAT3SOS1 | |
| SCHEMBL16613064 | 0.88 | AADAT (0.46) | AADATKYAT1KYAT3 | |
| SCHEMBL3778827 | 0.86 | AADAT (0.53) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL3779729 | 0.85 | AADAT (0.52) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL16613068 | 0.85 | AADAT (0.52) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL16613187 | 0.85 | AADAT (0.46) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL16613022 | 0.84 | AADAT (0.51) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL3773972 | 0.84 | AADAT (0.59) | AADATKYAT1KYAT3 | |
| SCHEMBL3806890 | 0.84 | AADAT (0.65) | AADATKYAT1KYAT3GOT1 | |
| SCHEMBL3770847 | 0.84 | AADAT (0.65) | AADATKYAT1KYAT3GOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443092-B1 | BICYCLIC AND TRICYCLIC COMPOUNDS AS KAT II INHIBITORS | PFIZER (US) | 2015-04-08 | — | — | EP | disclosed |