SCHEMBL16613458

SCHEMBL16613458

c1ccc(-n2ccc3c2ccc2c4ccccc4n(-c4nc(-c5ccccn5)c5ccsc5n4)c23)cc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.35
KRAS P01116 1/20 0.34
VCP P55072 1/20 0.33
ADORA1 P30542 3/20 0.31
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613700 0.88 ADORA2A (0.33) MCL1KRASADORA2A
SCHEMBL16613453 0.88 VCP (0.35) VCPADORA2A
SCHEMBL16613726 0.86 ADORA1 (0.41) MCL1ADORA1ADORA2A
SCHEMBL16613468 0.86 VCP (0.34) VCPADORA2A
SCHEMBL16613264 0.86 MCL1 (0.38) MCL1
SCHEMBL16613529 0.85 VCP (0.33) VCP
SCHEMBL16613544 0.84 VCP (0.33) VCP
SCHEMBL16613487 0.84 VCP (0.33) VCP
SCHEMBL16613419 0.84 VCP (0.33) VCP
SCHEMBL16613545 0.84 ADORA2A (0.36) VCPADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed