SCHEMBL16613591

SCHEMBL16613591

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4nc(-c5ccc(-c6cccc7ccccc67)cc5)c5ccsc5n4)ccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
VCP P55072 1/20 0.32
ALK Q9UM73 1/20 0.31
PTGER4 P35408 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
POLB P06746 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
NPY5R Q15761 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
TLR4 O00206 1/20 0.30
TUBB4A P04350 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613718 0.94 KDM4E (0.33) KDM4EATML3MBTL1VCPPTGER4
SCHEMBL16613564 0.94 KDM4E (0.36) KDM4EATML3MBTL1VCPPTGER4
SCHEMBL16613565 0.92 KDM4E (0.35) KDM4EATML3MBTL1VCPPTGER4
SCHEMBL16613566 0.91 KDM4E (0.40) KDM4EATML3MBTL1VCPPTGER4
SCHEMBL16613722 0.90 KDM4E (0.39) KDM4EATML3MBTL1VCPPTGER4
SCHEMBL16613656 0.90 VCP (0.35) VCPCA12CA1CA2CA9
SCHEMBL16613717 0.89 KDM4E (0.37) KDM4EATML3MBTL1VCPPTGER4
SCHEMBL16613592 0.88 KDM4E (0.36) KDM4EATML3MBTL1VCPPTGER4
SCHEMBL16613716 0.88 KDM4E (0.38) KDM4EATML3MBTL1VCPPTGER4
SCHEMBL16404904 0.86 KDM4E (0.40) KDM4EATML3MBTL1PTGER4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed