SCHEMBL16614075

SCHEMBL16614075

Nc1nc(-c2ccc(-c3cccc4ccccc34)cc2)c2ccccc2n1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 14/20 0.70
NUDT1 P36639 3/20 0.70
SCN9A Q15858 1/20 0.56
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ATM Q13315 1/20 0.49
DCPS Q96C86 1/20 0.47
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12281655 0.83 ADORA2A (0.92) ADORA2ANUDT1SCN9AMEN1KMT2A
SCHEMBL421987 0.83 ADORA2A (1.00) ADORA2ANUDT1SCN9AMEN1KMT2A
SCHEMBL21667647 0.83 ATM (0.62) ADORA2ANUDT1MEN1KMT2AATM
Hydrochloric Acid SCHEMBL27344186 0.81 ADORA2A (0.96) ADORA2ANUDT1SCN9AMEN1KMT2A
SCHEMBL1755393 0.81 KDM4E (0.65) ADORA2ANUDT1MEN1KMT2AATM
SCHEMBL16671089 0.81 HDAC8 (0.44) ADORA2ANUDT1MEN1KMT2AATM
SCHEMBL30564904 0.81 KDM4E (0.65) ADORA2ANUDT1MEN1KMT2AATM
SCHEMBL18119034 0.81 ADORA2A (0.49) ADORA2ANUDT1MEN1KMT2AATM
SCHEMBL25801266 0.80 ENPP3 (0.49) MEN1KMT2ACA12CA1CA2
SCHEMBL19057605 0.78 HDAC8 (0.41) ADORA2ANUDT1MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017188597-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2017-11-02 WO disclosed
WO-2015047018-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed