SCHEMBL1661430

SCHEMBL1661430

CCCCC(=O)c1cc[c]cc1

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 8/20 0.63
HTR7 P34969 1/20 0.61
STS P08842 5/20 0.50
L3MBTL1 Q9Y468 3/20 0.47
NPC1 O15118 2/20 0.46
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5539337 0.94 HSD17B3 (0.65) HSD17B3HTR7STSL3MBTL1LMNA
Zinc Chloride SCHEMBL28129863 0.93 HSD17B3 (0.56) HSD17B3HTR7STSL3MBTL1NPC1
SCHEMBL9564630 0.92 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1LMNA
SCHEMBL9564620 0.92 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1LMNA
SCHEMBL4611644 0.92 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1LMNA
SCHEMBL9564629 0.92 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1LMNA
SCHEMBL4956948 0.92 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1LMNA
SCHEMBL9564653 0.92 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1LMNA
SCHEMBL9564617 0.92 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1LMNA
SCHEMBL9564644 0.92 HSD17B3 (0.66) HSD17B3HTR7STSL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102653543-A Preparation method, biological activity and application of 3-substituted type Jolkinolide compound UNIV CHINA PHARMA 2012-09-05 CN claimed
EP-1576110-A4 CELL MIGRATION INHIBITING COMPOSITIONS AND METHODS AND COMPOSITIONS FOR TREATING CANCER AVOLIX PHARMACEUTICALS (US) 2007-11-07 EP claimed
EP-1576110-A2 CELL MIGRATION INHIBITING COMPOSITIONS AND METHODS AND COMPOSITIONS FOR TREATING CANCER Avolix Pharmaceuticals (US) 2005-09-21 EP claimed
WO-2003102153-A2 CELL MIGRATION INHIBITING COMPOSITIONS AND METHODS AND COMPOSITIONS FOR TREATING CANCER AVOLIX PHARMACEUTICALS (US) 2003-12-11 WO claimed
CN-111936577-A Polyester resin composition 三菱瓦斯化学株式会社 2020-11-13 CN disclosed
CN-109415493-A Sealing material for semiconductor 太阳油墨制造株式会社 2019-03-01 CN disclosed
CN-108419438-A Coloured composition 株式会社艾迪科 2018-08-17 CN disclosed
CN-108404690-A A kind of preparation method of MOF- polyimide composite films material 哈尔滨工业大学 2018-08-17 CN disclosed
CN-108369831-A Conductive paste 株式会社艾迪科 2018-08-03 CN disclosed
CN-107636024-A Composition 株式会社艾迪科 2018-01-26 CN disclosed
US-9048442-B2 Composition containing a metal complex and organic compound, and light-emitting element using said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-06-02 US disclosed
EP-2305772-B1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT EMITTING ELEMENT USING SAID COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-05-20 EP disclosed
US-5270281-A Chromogenic compound MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-12-14 US disclosed
EP-0569328-A1 Bis-phosphite stabilized compositions CIBA-GEIGY AG (CH) 1993-11-10 EP disclosed
EP-0534257-A1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
EP-0524419-A1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-27 EP disclosed
EP-0511879-A1 Pyrazine derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-04 EP disclosed
US-5101035-A Thermal printing, improved migration properties, color intensity, water and chemical resistance BASF AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed
EP-0415203-A2 Thiazole dyes of the merocyanine type and a thermal transfer process using these dyes BASF Aktiengesellschaft (DE) 1991-03-06 EP disclosed
EP-0192167-A1 Use of thio-substitued ketones as photoinitiators MERCK PATENT GmbH (DE) 1986-08-27 EP disclosed