SCHEMBL16614437

SCHEMBL16614437

NN(c1ccc(-c2ccccn2)cc1)c1ccc(-c2ccccn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
LMNA P02545 3/20 0.50
CYP1A2 P05177 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
CYP2D6 P10635 1/20 0.46
CYP19A1 P11511 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CYP2A6 P11509 1/20 0.46
NPC1 O15118 5/20 0.43
TP53 P04637 4/20 0.43
RAB9A P51151 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16614443 0.93 NPC1 (0.45) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL16614440 0.91 CYP2A6 (0.43) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL16614439 0.86 CYP2A6 (0.63) CYP1A2CYP19A1CYP2A6NPC1TP53
SCHEMBL27364973 0.85 CYP1A2 (0.47) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL30909388 0.83 KDM4E (0.54) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL30989133 0.82 KDM4E (0.72) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL30989132 0.82 KDM4E (0.72) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL1566968 0.82 KDM4E (0.72) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL29984274 0.80 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL13458076 0.80 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015046982-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed