Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17449533 | 0.98 | PRSS1 (0.59) | PRSS1PRSS2PRSS3KMODHODH | |
| SCHEMBL16615090 | 0.97 | PRSS1 (0.58) | PRSS1PRSS2PRSS3KMODHODH | |
| SCHEMBL17449577 | 0.84 | PRSS1 (0.41) | PRSS1PRSS2PRSS3KMODHODH | |
| SCHEMBL16173855 | 0.82 | WDR5 (0.55) | PRSS1PRSS2PRSS3DHODHWDR5 | |
| SCHEMBL4535484 | 0.81 | F2 (0.48) | PRSS1PRSS2PRSS3WDR5F2 | |
| SCHEMBL26498663 | 0.79 | PRSS1 (0.49) | PRSS1PRSS2PRSS3KMODHODH | |
| SCHEMBL26498886 | 0.79 | PRSS1 (0.49) | PRSS1PRSS2PRSS3KMODHODH | |
| SCHEMBL18088798 | 0.77 | PARP1 (0.52) | — | |
| SCHEMBL17345674 | 0.76 | PRSS1 (0.62) | PRSS1PRSS2PRSS3KMODHODH | |
| SCHEMBL22373684 | 0.76 | PRSS1 (0.62) | PRSS1PRSS2PRSS3KMODHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015046916-A1 | A COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2015-04-02 | — | — | WO | disclosed |