Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 7/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16604769 | 1.00 | ALDH1A1 (0.56) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL15873777 | 0.91 | ALDH1A1 (0.60) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL15873821 | 0.91 | ALDH1A1 (0.60) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL30234010 | 0.89 | ALDH1A1 (0.58) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL17209369 | 0.86 | ALDH1A1 (0.59) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL22228031 | 0.85 | ALDH1A1 (0.43) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL22228032 | 0.85 | ALDH1A1 (0.43) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL16604750 | 0.82 | ALDH1A1 (0.63) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL16604745 | 0.82 | ALDH1A1 (0.63) | ALDH1A1GAATSHRDPP4DPP7 | |
| SCHEMBL854004 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAATSHRDPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329498-A1 | IRAK INHIBITORS AND USES THEREOF | NIMBUS IRIS, INC. | 2015-11-19 | — | — | US | disclosed |
| WO-2015048281-A1 | IRAK INHIBITORS AND USES THEREOF | NIMBUS IRIS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329498-A1 | IRAK INHIBITORS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | ALDH1A1 3351/4885GAA 1372/4885TSHR 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.