Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996207 | 0.92 | PTGS2 (0.43) | LPLLIPGPTGS2ESR1ADRA2A | |
| SCHEMBL16682984 | 0.90 | PTGS2 (0.44) | LPLLIPGPTGS2ESR1ADRA2A | |
| SCHEMBL16615343 | 0.88 | RARB (0.48) | LPLLIPGPTGS2ESR1ADRA2A | |
| SCHEMBL16615338 | 0.88 | PTGS2 (0.46) | LPLLIPGPTGS2ESR1ADRA2A | |
| SCHEMBL16615349 | 0.86 | RARB (0.47) | LPLLIPGPTGS2ESR1ADRA2A | |
| SCHEMBL13197742 | 0.85 | SKP2 (0.44) | LPLLIPGCYP3A4ALDH1A1TP53 | |
| SCHEMBL12313694 | 0.85 | SKP2 (0.46) | PTGS2CYP3A4TP53KCNH2CYP2D6 | |
| SCHEMBL16682950 | 0.84 | SKP2 (0.42) | LPLLIPGPTGS2ESR1ADRA2A | |
| SCHEMBL12593358 | 0.83 | SKP2 (0.47) | PTGS2CYP3A4ALDH1A1TP53KCNH2 | |
| SCHEMBL15854847 | 0.83 | SKP2 (0.47) | PTGS2CYP3A4ALDH1A1TP53KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160218291-A1 | POLYMER AND ORGANIC LIGHT EMITTING DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2016-07-28 | — | — | US | disclosed |
| WO-2015044656-A1 | POLYMER AND ORGANIC LIGHT EMITTING DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2015-04-02 | — | — | WO | disclosed |