SCHEMBL16615751

CC(O)[C@@H]1NC(=O)[C@@H](NC(=O)[C@@H](N)CO)CCC(=O)NCCCC[C@@H](C(=O)N[C@@H](CO)C(=O)N(C)[C@@H](Cc2ccccc2)C(N)=O)NC(=O)[C@H](CO)NC1=O

nearest known ligand 0.47

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	SSTR5	P35346	5/20	0.47

▸	SSTR2	P30874	4/20	0.47

▸	SSTR4	P31391	4/20	0.47

▸	MC1R	Q01726	1/20	0.46

▸	SSTR1	P30872	4/20	0.43

▸	SSTR3	P32745	1/20	0.43

▸	SRC	P12931	1/20	0.42

▸	MLLT3	P42568	1/20	0.41

▸	MLLT1	Q03111	1/20	0.41

▸	OPRM1	P35372	1/20	0.40

▸	OPRD1	P41143	1/20	0.40

▸	OPRK1	P41145	1/20	0.40

▸	TERF2	Q15554	2/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16615864	0.87	SSTR5 (0.50)	SSTR5SSTR2SSTR4MC1RSSTR1
SCHEMBL16615856	0.86	SRC (0.42)	SSTR5SSTR2SSTR4MC1RSSTR1
SCHEMBL16615854	0.85	SSTR2 (0.50)	SSTR5SSTR2SSTR4MC1RSSTR1
SCHEMBL16691453	0.84	SRC (0.48)	SSTR5SSTR2SSTR4MC1RSSTR1
SCHEMBL16615904	0.84	SRC (0.48)	SSTR5SSTR2SSTR4MC1RSSTR1
SCHEMBL16691478	0.83	SRC (0.51)	SSTR5SSTR2SSTR4MC1RSRC
SCHEMBL16615594	0.82	MC1R (0.46)	SSTR5SSTR2SSTR4MC1RSRC
SCHEMBL16692279	0.82	SSTR2 (0.46)	SSTR5SSTR2SSTR4MC1RSSTR1
SCHEMBL16615868	0.81	MC1R (0.45)	SSTR5SSTR2SSTR4MC1RSSTR1
SCHEMBL16691466	0.81	SRC (0.47)	SSTR5SSTR2SSTR4SSTR1SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2015044900-A1	THERAPEUTIC IMMUNOMODULATING COMPOUNDS	AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN)	2015-04-02	—	—	WO	disclosed