Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | NPY4R | P50391 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615764 | 0.93 | MC1R (0.46) | MC1RSRCSSTR2SSTR4SSTR5 | |
| SCHEMBL16615888 | 0.90 | MC1R (0.38) | MC1RSRCOPRM1OPRD1OPRK1 | |
| SCHEMBL16615750 | 0.89 | SRC (0.47) | MC1RSRCSSTR2SSTR4SSTR5 | |
| SCHEMBL16615743 | 0.86 | TERF2 (0.42) | MC1RSRCSSTR2SSTR4SSTR5 | |
| SCHEMBL16615594 | 0.86 | MC1R (0.46) | MC1RSRCSSTR2SSTR4SSTR5 | |
| SCHEMBL16615765 | 0.84 | STAT3 (0.42) | MC1RSRCSSTR2SSTR4SSTR5 | |
| SCHEMBL16691478 | 0.84 | SRC (0.51) | MC1RSRCSSTR2SSTR4SSTR5 | |
| SCHEMBL16615904 | 0.84 | SRC (0.48) | MC1RSRCSSTR2SSTR4SSTR5 | |
| SCHEMBL16615899 | 0.84 | SIRT2 (0.39) | MC1ROPRM1OPRD1OPRK1MMP1 | |
| SCHEMBL16615891 | 0.83 | SSTR1 (0.36) | MC1RSRCSSTR2SSTR4SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044900-A1 | THERAPEUTIC IMMUNOMODULATING COMPOUNDS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-04-02 | — | — | WO | disclosed |