SCHEMBL16615752

CC(O)[C@@H]1NC(=O)[C@@H](NC[C@@H](N)CO)CCC(=O)NCCCC[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)NC[C@H](CO)NC1=O

nearest known ligand 0.40

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	SRC	P12931	1/20	0.40

▸	CCKBR	P32239	6/20	0.40

▸	STAT3	P40763	2/20	0.39

▸	MLLT3	P42568	2/20	0.38

▸	MLLT1	Q03111	1/20	0.38

▸	SSTR2	P30874	1/20	0.37

▸	SSTR4	P31391	1/20	0.37

▸	SSTR5	P35346	1/20	0.37

▸	REN	P00797	3/20	0.37

▸	MC1R	Q01726	1/20	0.36

▸	NPY4R	P50391	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16615755	0.91	STAT3 (0.43)	SRCCCKBRSTAT3MLLT3MLLT1
SCHEMBL16615859	0.90	SRC (0.48)	SRCCCKBRSTAT3MLLT3MLLT1
SCHEMBL16691478	0.83	SRC (0.51)	SRCCCKBRSTAT3MLLT3MLLT1
SCHEMBL16615893	0.81	MMP1 (0.39)	SRCMLLT3MLLT1
SCHEMBL16691494	0.81	SRC (0.49)	SRCCCKBRSTAT3SSTR2SSTR4
SCHEMBL16691476	0.80	SRC (0.49)	SRCCCKBRSTAT3MLLT3MLLT1
SCHEMBL16615904	0.80	SRC (0.48)	SRCCCKBRSTAT3MLLT3MLLT1
SCHEMBL16691453	0.80	SRC (0.48)	SRCCCKBRSTAT3MLLT3MLLT1
SCHEMBL16691493	0.80	SRC (0.51)	SRCCCKBRSTAT3SSTR2SSTR4
SCHEMBL16691495	0.80	SRC (0.48)	SRCCCKBRSTAT3MLLT3SSTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2015044900-A1	THERAPEUTIC IMMUNOMODULATING COMPOUNDS	AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN)	2015-04-02	—	—	WO	disclosed