Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615896 | 0.88 | MMP1 (0.41) | POLBL3MBTL1TDP1SIRT2SIRT1 | |
| SCHEMBL16615893 | 0.88 | MMP1 (0.39) | POLBL3MBTL1TDP1SIRT2SIRT1 | |
| SCHEMBL16691482 | 0.87 | POLB (0.44) | POLBL3MBTL1TDP1SIRT2SIRT1 | |
| SCHEMBL16691453 | 0.86 | SRC (0.48) | POLBL3MBTL1TDP1MMP1MMP9 | |
| SCHEMBL16691481 | 0.85 | SRC (0.43) | POLBL3MBTL1TDP1SIRT2SIRT1 | |
| SCHEMBL16691478 | 0.84 | SRC (0.51) | POLBL3MBTL1TDP1MMP1MMP9 | |
| SCHEMBL16691497 | 0.83 | SRC (0.56) | POLBL3MBTL1TDP1SRCKLK7 | |
| SCHEMBL16691466 | 0.83 | SRC (0.47) | POLBL3MBTL1TDP1SIRT2SIRT1 | |
| SCHEMBL16615904 | 0.83 | SRC (0.48) | POLBL3MBTL1TDP1MMP1MMP9 | |
| SCHEMBL16691494 | 0.82 | SRC (0.49) | POLBL3MBTL1TDP1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044900-A1 | THERAPEUTIC IMMUNOMODULATING COMPOUNDS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-04-02 | — | — | WO | disclosed |