SCHEMBL16616060

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16616262	0.85	SLC6A3 (0.50)	ALDH1A1L3MBTL1SLC6A4SLC6A3SOS1
	SCHEMBL16055062	0.83	MAPT (0.44)	ALPLALDH1A1SLC6A4SLC6A3POLB
	SCHEMBL24515856	0.83	SOS1 (0.43)	ALDH1A1L3MBTL1SOS1DHODHSMN1; SMN2
	SCHEMBL16624251	0.81	SLC6A3 (0.39)	SLC6A4SLC6A3SOS1DHODHMAPT
	SCHEMBL16616086	0.81	SLC6A4 (0.47)	ALPLALDH1A1SLC6A4SLC6A3MKNK1
	SCHEMBL16616176	0.79	FFAR4 (0.52)	ALDH1A1L3MBTL1SMN1; SMN2MAPTNPC1
	SCHEMBL25793610	0.78	FFAR4 (0.50)	ALDH1A1L3MBTL1SLC6A4SLC6A3MKNK1
	SCHEMBL24515511	0.72	SOS1 (0.43)	ALDH1A1L3MBTL1SOS1MAPTLMNA
	SCHEMBL16624234	0.72	TTR (0.39)	ALDH1A1DHODHLMNAHPGDMEN1
	SCHEMBL24717384	0.72	KDM4E (0.42)	ALDH1A1SOS1POLBLMNAPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.