Benzene

Benzene

SCHEMBL16616141

C=CC(=O)O.C=CC(=O)O.c1ccccc1.c1ccccc1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.83
AKT1 P31749 1/20 0.48
ALOX15 P16050 3/20 0.46
HSD17B10 Q99714 2/20 0.46
TSHR P16473 7/20 0.44
ALDH1A1 P00352 6/20 0.44
FGFR4 P22455 1/20 0.44
TGM2 P21980 2/20 0.42
TP53 P04637 2/20 0.40
EGLN1 Q9GZT9 1/20 0.40
EGLN3 Q9H6Z9 1/20 0.40
MAPK1 P28482 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
EGFR P00533 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL9277306 1.00 LMNA (0.83) LMNAAKT1ALOX15HSD17B10TSHR
Benzene SCHEMBL27372521 1.00 LMNA (0.83) LMNAAKT1ALOX15HSD17B10TSHR
Benzene SCHEMBL8219818 0.96 LMNA (0.77) LMNAAKT1ALOX15HSD17B10TSHR
Benzene SCHEMBL28063477 0.96 LMNA (0.77) LMNAAKT1ALOX15HSD17B10TSHR
Benzene SCHEMBL27532442 0.96 LMNA (0.77) LMNAAKT1ALOX15HSD17B10TSHR
Benzene SCHEMBL27534843 0.96 LMNA (0.77) LMNAAKT1ALOX15HSD17B10TSHR
Benzene SCHEMBL27690841 0.96 LMNA (0.77) LMNAAKT1ALOX15HSD17B10TSHR
Benzene SCHEMBL28841097 0.96 LMNA (0.77) LMNAAKT1ALOX15HSD17B10TSHR
Benzene SCHEMBL1740590 0.93 LMNA (0.71) LMNAAKT1ALOX15HSD17B10TSHR
Acrylic Acid SCHEMBL8460539 0.91 LMNA (1.00) LMNAAKT1ALOX15HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150099817-A1 MOULDED PARTS MADE OF PMMA POWDER AS SIMPLE DOSING AID IN THE MANUFACTURE OF DENTAL PROSTHESES HERAEUS KULZER GMBH (DE) 2015-04-09 US disclosed
CN-100377400-C Catalyst for fuel cell, method for preparation thereof and fuel cell FUJITSU LTD (JP) 2008-03-26 CN disclosed