Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 5/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16616215 | 1.00 | TNFRSF1A (0.57) | TNFRSF1AABCB1ABCG2TEKKRAS | |
| SCHEMBL16616603 | 0.94 | ABCB1 (0.56) | TNFRSF1AABCB1ABCG2KRASCYP1A1 | |
| SCHEMBL16616602 | 0.94 | ABCB1 (0.56) | TNFRSF1AABCB1ABCG2KRASCYP1A1 | |
| SCHEMBL16616875 | 0.92 | ABCB1 (0.52) | TNFRSF1AABCB1ABCG2KRASCYP1A1 | |
| SCHEMBL16616870 | 0.92 | ABCB1 (0.52) | TNFRSF1AABCB1ABCG2KRASCYP1A1 | |
| SCHEMBL16616421 | 0.92 | POLB (0.56) | TNFRSF1AABCB1ABCG2KRASMEN1 | |
| SCHEMBL16616423 | 0.92 | POLB (0.56) | TNFRSF1AABCB1ABCG2KRASMEN1 | |
| SCHEMBL16616909 | 0.91 | KRAS (0.52) | TNFRSF1AABCB1ABCG2KRASCYP1A1 | |
| SCHEMBL16616913 | 0.91 | KRAS (0.52) | TNFRSF1AABCB1ABCG2KRASCYP1A1 | |
| SCHEMBL16616607 | 0.91 | ABCB1 (0.51) | TNFRSF1AABCB1ABCG2KRASCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006451-B1 | 2-anilinonicotinyl based chalcones useful as potential anticancer agents and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-14 | — | — | US | disclosed |
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | HCCS, WEE2, WEE1 | TNFRSF1A 1747/4885ABCB1 537/4885ABCG2 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.