SCHEMBL16616602

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16616603	1.00	ABCB1 (0.56)	ABCB1ABCG2TNFRSF1AKRASCYP1A1
	SCHEMBL16616532	0.94	ABCG2 (0.54)	ABCB1ABCG2TNFRSF1ACYP1A1CYP1A2
	SCHEMBL16616533	0.94	ABCG2 (0.54)	ABCB1ABCG2TNFRSF1ACYP1A1CYP1A2
	SCHEMBL16616869	0.94	ABCB1 (0.52)	ABCB1ABCG2TNFRSF1AKRASCYP1A1
	SCHEMBL16616871	0.94	ABCB1 (0.52)	ABCB1ABCG2TNFRSF1AKRASCYP1A1
	SCHEMBL16616215	0.94	TNFRSF1A (0.57)	ABCB1ABCG2TNFRSF1AKRASCYP1A1
	SCHEMBL16616217	0.94	TNFRSF1A (0.57)	ABCB1ABCG2TNFRSF1AKRASCYP1A1
	SCHEMBL16616238	0.92	CA1 (0.58)	ABCB1ABCG2KRASCYP1A1CYP1A2
	SCHEMBL16616372	0.92	KRAS (0.57)	ABCG2TNFRSF1AKRASCYP1A1CYP1A2
	SCHEMBL16616379	0.92	KRAS (0.57)	ABCG2TNFRSF1AKRASCYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.