Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.73 |
| ▸ | S1PR3 | Q99500 | 13/20 | 0.73 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1661536 | 0.99 | S1PR1 (0.72) | S1PR1S1PR3S1PR5DRD3 | |
| SCHEMBL1661579 | 0.94 | S1PR1 (0.81) | S1PR1S1PR3S1PR5DRD3 | |
| SCHEMBL15163481 | 0.92 | S1PR1 (0.64) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1661493 | 0.91 | S1PR1 (0.79) | S1PR1S1PR3S1PR5DRD3 | |
| SCHEMBL1661662 | 0.91 | S1PR1 (0.89) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3420401 | 0.91 | S1PR1 (0.89) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1662656 | 0.91 | S1PR1 (0.89) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL1661345 | 0.90 | S1PR1 (0.88) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL1661533 | 0.90 | S1PR1 (0.88) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL1661347 | 0.90 | S1PR1 (0.88) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011524906-A | — | — | 2011-09-08 | — | — | JP | claimed |
| EP-2306994-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | Amgen, Inc (US) | 2011-04-13 | — | — | EP | claimed |
| WO-2009154775-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. (US) | 2009-12-23 | — | — | WO | claimed |