SCHEMBL16616680

SCHEMBL16616680

CCOC(=O)CCNCC(F)F

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.45
GAA P10253 1/20 0.45
SI P14410 1/20 0.45
MGAM2 Q2M2H8 1/20 0.45
CYP1A2 P05177 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
LTA4H P09960 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28696630 0.83 MGAM (0.46) MGAMGAASIMGAM2L3MBTL1
SCHEMBL7428536 0.83 MGAM (0.46) MGAMGAASIMGAM2CYP1A2
SCHEMBL17725604 0.82 TSHR (0.48) MGAMGAASIMGAM2KMT2A
SCHEMBL4464939 0.82 GAA (0.59) MGAMGAASIMGAM2CYP1A2
Hydrochloric Acid SCHEMBL7567529 0.81 MGAM (0.45) MGAMGAASIMGAM2CYP1A2
SCHEMBL15391903 0.81 GAA (0.48) MGAMGAASIMGAM2CYP1A2
SCHEMBL11119128 0.80 L3MBTL1 (0.44) MGAMGAASIMGAM2CYP1A2
SCHEMBL22223252 0.80 MGAM (0.43) MGAMGAASIMGAM2CYP1A2
SCHEMBL11231751 0.80 CYP1A2 (0.44) MGAMGAASIMGAM2CYP1A2
Hydrochloric Acid SCHEMBL11851530 0.80 GAA (0.56) MGAMGAASIMGAM2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12077510-B2 Carboxylic acid compounds Sumitomo Pharma Co., Ltd. (JP) 2024-09-03 US disclosed
US-20220267282-A1 CARBOXYLIC ACID COMPOUNDS SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2022-08-25 US disclosed
US-11299465-B2 Carboxylic acid compounds SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2022-04-12 US disclosed
US-11299465-B2 Carboxylic acid compounds SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2022-04-12 US disclosed
US-20200317623-A1 CARBOXYLIC ACID COMPOUNDS SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2020-10-08 US disclosed
US-20200317623-A1 CARBOXYLIC ACID COMPOUNDS SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2020-10-08 US disclosed
US-10562861-B2 Carboxylic acid compounds SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2020-02-18 US disclosed
US-10562861-B2 Carboxylic acid compounds SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2020-02-18 US disclosed
US-20190119220-A1 CARBOXYLIC ACID COMPOUNDS SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2019-04-25 US disclosed
US-20190119220-A1 CARBOXYLIC ACID COMPOUNDS SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2019-04-25 US disclosed
US-20160251319-A1 CARBOXYLIC ACID COMPOUNDS SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-09-01 US disclosed
US-20160251319-A1 CARBOXYLIC ACID COMPOUNDS SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-09-01 US disclosed
US-20160251319-A1 CARBOXYLIC ACID COMPOUNDS SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-09-01 US disclosed
US-9376398-B2 Carboxylic acid compounds SUMITOMO DAINIPPON PHARMA CO., LTD (JP) 2016-06-28 US disclosed
US-9376398-B2 Carboxylic acid compounds SUMITOMO DAINIPPON PHARMA CO., LTD (JP) 2016-06-28 US disclosed
US-9376398-B2 Carboxylic acid compounds SUMITOMO DAINIPPON PHARMA CO., LTD (JP) 2016-06-28 US disclosed
US-20150099770-A1 CARBOXYLIC ACID COMPOUNDS Sumitomo Pharma Co., Ltd. (JP) 2015-04-09 US disclosed
US-20150099770-A1 CARBOXYLIC ACID COMPOUNDS Sumitomo Pharma Co., Ltd. (JP) 2015-04-09 US disclosed
US-20150099770-A1 CARBOXYLIC ACID COMPOUNDS Sumitomo Pharma Co., Ltd. (JP) 2015-04-09 US disclosed
CN-104302628-A Carboxylic acid compounds DAINIPPON SUMITOMO PHARMA CO 2015-01-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150099770-A1 CARBOXYLIC ACID COMPOUNDS C9, SUCNR1, C3AR1 MGAM 1677/4885GAA 181/4885SI 1366/4885
US-20160251319-A1 CARBOXYLIC ACID COMPOUNDS C9, SUCNR1, C3AR1 MGAM 1677/4885GAA 181/4885SI 1366/4885
US-12077510-B2 Carboxylic acid compounds C9, C3AR1, SUCNR1 MGAM 1508/4885GAA 225/4885SI 1255/4885
US-20200317623-A1 CARBOXYLIC ACID COMPOUNDS C9, C3AR1, SUCNR1 MGAM 1508/4885GAA 225/4885SI 1255/4885
US-20190119220-A1 CARBOXYLIC ACID COMPOUNDS C9, C3AR1, SUCNR1 MGAM 1508/4885GAA 225/4885SI 1255/4885
US-11299465-B2 Carboxylic acid compounds C9, C3AR1, SUCNR1 MGAM 1508/4885GAA 225/4885SI 1255/4885
US-20220267282-A1 CARBOXYLIC ACID COMPOUNDS C9, C3AR1, SUCNR1 MGAM 1508/4885GAA 225/4885SI 1255/4885
US-10562861-B2 Carboxylic acid compounds C9, C3AR1, SUCNR1 MGAM 1508/4885GAA 225/4885SI 1255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.