Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL3960 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29723505 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29367714 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL9879420 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL9878595 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL9879191 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29521813 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL3467 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL3468 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL9647802 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240058376-A1 | COMPOSITION OF MATTER, SYSTEM, AND METHOD FOR ENHANCED MAGNESIUM UPTAKE, RETENTION, AND SYNERGISTIC ACTIONS | RMJH Holdings, LLC (US) | 2024-02-22 | — | — | US | claimed |
| WO-2024040141-A1 | COMPOSITION OF MATTER, SYSTEM, AND METHOD FOR ENHANCED MAGNESIUM UPTAKE, RETENTION, AND SYNERGISTIC ACTIONS | RMJ HOLDINGS, LLC (US) | 2024-02-22 | — | — | WO | claimed |
| CN-117279628-A | Ionic liquid salts of active pharmaceutical ingredients | 葛兰素史克消费保健（美国）控股有限责任公司 | 2023-12-22 | — | — | CN | claimed |
| US-11712449-B1 | Composition of matter, system, and method for enhanced magnesium uptake, retention, and synergistic actions | RMJH Holdings, LLC (US) | 2023-08-01 | — | — | US | claimed |
| US-12109227-B2 | Composition of matter, system, and method for enhanced magnesium uptake, retention, and synergistic actions | RMJH Holdings, LLC (US) | 2024-10-08 | — | — | US | disclosed |
| WO-2024040141-A1 | COMPOSITION OF MATTER, SYSTEM, AND METHOD FOR ENHANCED MAGNESIUM UPTAKE, RETENTION, AND SYNERGISTIC ACTIONS | RMJ HOLDINGS, LLC (US) | 2024-02-22 | — | — | WO | disclosed |
| US-20240058376-A1 | COMPOSITION OF MATTER, SYSTEM, AND METHOD FOR ENHANCED MAGNESIUM UPTAKE, RETENTION, AND SYNERGISTIC ACTIONS | RMJH Holdings, LLC (US) | 2024-02-22 | — | — | US | disclosed |
| CN-117279628-A | Ionic liquid salts of active pharmaceutical ingredients | 葛兰素史克消费保健（美国）控股有限责任公司 | 2023-12-22 | — | — | CN | disclosed |
| US-11712449-B1 | Composition of matter, system, and method for enhanced magnesium uptake, retention, and synergistic actions | RMJH Holdings, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| EP-2483092-A1 | SYSTEM AND METHOD FOR MONITORING THE TEMPERATURE OF THE PASSENGER COMPARTMENT OF A MOTOR VEHICLE | RENAULT S.A.S. (FR) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011039447-A1 | SYSTEM AND METHOD FOR MONITORING THE TEMPERATURE OF THE PASSENGER COMPARTMENT OF A MOTOR VEHICLE | RENAULT S.A.S. (FR) | 2011-04-07 | — | — | WO | disclosed |
| US-20050037033-A1 | Microbicidal compositions and methods and use | PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH (US) | 2005-02-17 | — | — | US | disclosed |
| WO-2004105662-A1 | MICROBICIDAL COMPOSITIONS AND METHODS OF USE | PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH (US) | 2004-12-09 | — | — | WO | disclosed |