Salicylic Acid

Salicylic Acid

SCHEMBL3468

C[N+](C)(C)CCO.O=C([O-])c1ccccc1O.O=C([O-])c1ccccc1O.O=C([O-])c1ccccc1O.[Mg+2]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.59
ALDH1A1 P00352 6/20 0.59
HPGD P15428 6/20 0.59
SMN1; SMN2 Q16637 3/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
HMGB1 P09429 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
CA14 Q9ULX7 1/20 0.40
LMNA P02545 4/20 0.40
TSHR P16473 3/20 0.40
GAA P10253 4/20 0.39
MAPT P10636 5/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL29521813 1.00 KDM4E (0.59) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL4179751 0.98 KDM4E (0.58) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29723505 0.98 KDM4E (0.61) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL3960 0.98 KDM4E (0.61) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL1661720 0.98 KDM4E (0.61) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL9879191 0.97 KDM4E (0.59) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL3467 0.97 KDM4E (0.59) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL9879420 0.97 KDM4E (0.59) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29367714 0.97 KDM4E (0.59) KDM4EALDH1A1HPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL9878595 0.97 KDM4E (0.59) KDM4EALDH1A1HPGDSMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11887 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122028914-A Combination therapy for autoimmune disorders 拜奥海芬治疗学有限公司 2026-05-12 CN claimed
US-20260115209-A1 COMBINATION THERAPY INCLUDING COX-2 INHIBITOR FOR THE TREATMENT OF CANCER UNIV CALIFORNIA (US) 2026-04-30 US claimed
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
WO-2025081174-A1 COMBINATION TREATMENT OF AUTOIMMUNE DISORDERS BIOHAVEN THERAPEUTICS LTD. (VG) 2025-04-17 WO claimed
CN-119792640-A Filler composition, preparation method and application thereof 渼颜空间(河北)生物科技有限公司 2025-04-11 CN claimed
WO-2025076059-A1 ROCAGLATE DERIVATIVES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-04-10 WO claimed
WO-2025066019-A1 TOPICAL DELIVERY COMPOSITIONS COMPRISING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ANDROS PHARMACEUTICALS CO., LTD. (CN) 2025-04-03 WO claimed
EP-4529917-A1 TOPICAL DELIVERY COMPOSITIONS COMPRISING NON-STEROIDAL ANTI-INLAMMATORY DRUGS Andros Pharmaceuticals Co., Ltd. (TW) 2025-04-02 EP claimed
WO-1996006640-A1 BIOADHESIVE-WOUND HEALING COMPOSITION WARNER-LAMBERT COMPANY (US) 1996-03-07 WO claimed
WO-1996003149-A1 ANTIFUNGAL-WOUND HEALING COMPOSITIONS AND METHODS FOR PREPARING AND USING SAME WARNER-LAMBERT COMPANY (US) 1996-02-08 WO claimed
WO-1996000584-A1 ANTI-INFLAMMATORY WOUND HEALING COMPOSITIONS AND METHODS FOR PREPARING AND USING SAME WARNER-LAMBERT COMPANY (US) 1996-01-11 WO claimed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 WO claimed
EP-0642336-A1 USE OF NSIAD IN THE TREATMENT OF DEMENTIA UNIVERSITY OF BRITISH COLUMBIA (CA) 1995-03-15 EP claimed
WO-1993024115-A1 ANTI-RHEUMATOID ARTHRITIC DRUGS IN THE TREATMENT OF DEMENTIA THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1993-12-09 WO claimed
US-5192753-A Anti-rheumatoid arthritic drugs in the treatment of dementia SUN HEALTH CORPORATION, INC. 1993-03-09 US claimed
US-5164379-A Reduction of gastric irritation caused by medicines BRISTOL-MYERS COMPANY (US) 1992-11-17 US claimed
EP-0249561-B1 COMPOSITIONS USING LIPOSOME-ENCAPSULATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS THE LIPOSOME COMPANY, INC. (US) 1992-05-13 EP claimed
US-5043168-A Nonhygroscopic, antiarthritis agent, analgesic SIDMAK LABORATORIES, INC. (US) 1991-08-27 US claimed