SCHEMBL16617562

SCHEMBL16617562

CCN(CCc1ccccc1)c1cccc(N)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.51
MAOA P21397 2/20 0.51
NR1H2 P55055 2/20 0.51
NR1H3 Q13133 2/20 0.51
AOC3 Q16853 3/20 0.49
OPRM1 P35372 2/20 0.49
DRD3 P35462 2/20 0.49
CHRM2 P08172 1/20 0.49
HTR1A P08908 1/20 0.49
ADRA2A P08913 1/20 0.49
CHRM1 P11229 1/20 0.49
DRD1 P21728 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A4 P31645 1/20 0.49
ADRA1A P35348 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KCNH2 Q12809 1/20 0.49
TSHR P16473 1/20 0.46
CYP19A1 P11511 1/20 0.42
BCHE P06276 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16617453 0.92 KCNH2 (0.56) MAOBMAOANR1H2NR1H3AOC3
SCHEMBL16617287 0.89 MAOB (0.50) MAOBMAOANR1H2NR1H3AOC3
SCHEMBL10524794 0.83 TSHR (0.64) NR1H2NR1H3AOC3OPRM1DRD3
SCHEMBL9470917 0.83 NR1H2 (0.52) NR1H2NR1H3AOC3OPRM1DRD3
SCHEMBL28904547 0.82 TSHR (0.55) MAOBMAOANR1H2NR1H3AOC3
Hydrochloric Acid SCHEMBL6966627 0.82 MAOB (0.56) MAOBMAOANR1H2NR1H3AOC3
SCHEMBL16617493 0.82 CYP3A4 (0.47) TSHRTAAR1ALDH1A1CYP3A4
SCHEMBL11691833 0.81 MAPT (0.51) NR1H2NR1H3AOC3OPRM1DRD3
SCHEMBL29931735 0.81 ALDH1A1 (0.59) TSHRTAAR1ALDH1A1CYP3A4
SCHEMBL1413227 0.81 ALDH1A1 (0.59) TSHRTAAR1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828339-B1 CARBOXYLATE DYES MILLIKEN & CO (US) 2018-10-31 EP disclosed
US-9187717-B2 Carboxylate dyes MILLIKEN & COMPANY (US) 2015-11-17 US disclosed
US-20150099869-A1 Carboxylate Dyes MILLIKEN & COMPANY 2015-04-09 US disclosed
CN-104220535-A Carboxylate dyes MILLIKEN & CO 2014-12-17 CN disclosed