Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929573 | 0.98 | GAA (0.39) | GAAPOLBHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL1578848 | 0.98 | GAA (0.41) | GAAPOLBHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL29712141 | 0.87 | POLB (0.33) | GAAPOLBHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7770339 | 0.87 | POLB (0.33) | GAAPOLBHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL29712098 | 0.85 | POLB (0.32) | GAAPOLBHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL30187480 | 0.82 | — | — | |
| SCHEMBL14992914 | 0.75 | — | — | |
| SCHEMBL28793536 | 0.71 | POLB (0.32) | GAAPOLBHSP90AA1MAPK1SMN1; SMN2 | |
| SCHEMBL29355518 | 0.69 | GAA (0.36) | GAAPOLBHSP90AA1MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15104589 | 0.68 | POLB (0.35) | GAAPOLBHSP90AA1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747968-B | Cyclic 1, 2-dioxetane force response group, and synthetic method and application thereof | 天津大学 | 2023-01-24 | — | — | CN | claimed |
| US-10301443-B2 | Composite materials with desired characteristics | NANOCORE APS (DK) | 2019-05-28 | — | — | US | disclosed |
| CN-109415280-A | Oxy-Cope rearrangement for the preparation of pesticidal cyclopentenes | 巴斯夫欧洲公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-108699075-A | Spirocyclic derivatives | 巴斯夫欧洲公司 | 2018-10-23 | — | — | CN | disclosed |
| US-20180298154-A1 | DESIGN OF COMPOSITE MATERIALS WITH DESIRED CHARACTERISTICS | NANOCORE APS (DK) | 2018-10-18 | — | — | US | disclosed |
| CN-102627639-B | Macrocydic inhibitors of hepatitis c virus. | 爱尔兰詹森科学公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-103030636-B | The macrocyclic hcv inhibitors of hepatitis C virus | Ireland Jansen scientific company (IE) | 2016-03-02 | — | — | CN | disclosed |
| CN-105254637-A | PYRIMIDINE SUBSTITUTED MACROCYCLIC INHIBITORS | JANSSEN R & D IRELAND | 2016-01-20 | — | — | CN | disclosed |
| CN-101273052-B | Macrocyclic inhibitors of hepatitis C virus | JANSSEN R&D IRELAND (IE) | 2016-01-13 | — | — | CN | disclosed |
| CN-101273027-B | The macrocyclic hcv inhibitors of hepatitis C virus | JANSSEN R&D IRELAND (IE) | 2015-12-02 | — | — | CN | disclosed |
| CN-101273028-A | Macrocyclic inhibitors of hepatitis C virus | TIBOTEC PHARM LTD (IE) | 2008-09-24 | — | — | CN | disclosed |
| CN-101273052-A | Macrocyclic inhibitors of hepatitis C virus | TIBOTEC PHARM LTD (IE) | 2008-09-24 | — | — | CN | disclosed |
| CN-101273027-A | Macrocyclic inhibitors of hepatitis C virus | TIBOTEC PHARM LTD (IE) | 2008-09-24 | — | — | CN | disclosed |
| CN-101273042-A | Macrocyclic inhibitors of hepatitis C virus | TIBOTEC PHARM LTD (IE) | 2008-09-24 | — | — | CN | disclosed |
| CN-101233147-A | Macrocyclic inhibitors of hepatitis c virus | TIBOTEC PHARM LTD (IE) | 2008-07-30 | — | — | CN | disclosed |
| CN-101233137-A | Macrocylic inhibitors of hepatitis c virus | TIBOTEC PHARM LTD (IE) | 2008-07-30 | — | — | CN | disclosed |
| CN-101228169-A | Macrocyclic inhibitors of hepatitis c virus | TIBOTEC PHARM LTD (IE) | 2008-07-23 | — | — | CN | disclosed |
| CN-100384843-C | CGRP receptor antagonists | MERCK & CO INC (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-101039718-A | Cgrp receptor antagonists | MERCK & CO INC (US) | 2007-09-19 | — | — | CN | disclosed |
| CN-1802376-A | CGRP receptor antagonists | MERCK & CO INC (US) | 2006-07-12 | — | — | CN | disclosed |