Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 17/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567549 | 0.88 | OPRK1 (0.57) | OPRK1KCNH2OPRM1PARP1OPRD1 | |
| SCHEMBL1377451 | 0.88 | OPRK1 (0.57) | OPRK1KCNH2OPRM1PARP1OPRD1 | |
| SCHEMBL29440998 | 0.86 | AKR1C3 (0.53) | OPRK1 | |
| SCHEMBL28886212 | 0.85 | OPRK1 (0.45) | OPRK1KCNH2OPRM1PARP1OPRD1 | |
| SCHEMBL31130428 | 0.84 | KMT2A (0.48) | OPRK1 | |
| SCHEMBL17865584 | 0.83 | OPRK1 (0.67) | OPRK1KCNH2OPRM1PARP1OPRD1 | |
| SCHEMBL28935302 | 0.82 | EPHX2 (0.51) | OPRK1 | |
| SCHEMBL9596602 | 0.81 | OPRK1 (0.59) | OPRK1KCNH2OPRM1PARP1OPRD1 | |
| SCHEMBL30526930 | 0.80 | PARP10 (0.67) | OPRK1KCNH2PARP1PARP15PARP14 | |
| SCHEMBL10804966 | 0.79 | OPRK1 (0.60) | OPRK1KCNH2OPRM1PARP1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| CN-110256418-B | 1, 3-thiazol-2-yl substituted benzamides | 拜耳公司 | 2023-01-20 | — | — | CN | disclosed |
| WO-2015051043-A1 | BIARYL ACYL-SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS | AMGEN INC. (US) | 2015-04-09 | — | — | WO | disclosed |