Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678180 | 0.91 | SPHK1 (0.54) | SPHK1EPHX1CASP2NAAA | |
| SCHEMBL13649889 | 0.84 | POLB (0.42) | SPHK1EPHX1 | |
| SCHEMBL26017783 | 0.79 | SPHK1 (0.57) | SPHK1EPHX1CASP2NAAAHPGD | |
| SCHEMBL5813323 | 0.77 | POLB (0.44) | SPHK1EPHX1 | |
| SCHEMBL3427647 | 0.77 | SPHK1 (0.54) | SPHK1EPHX1CASP2NAAAHPGD | |
| SCHEMBL21941459 | 0.77 | SPHK1 (0.54) | SPHK1EPHX1CASP2NAAAHPGD | |
| SCHEMBL3682206 | 0.76 | SPHK1 (0.54) | SPHK1EPHX1CASP2NAAAHPGD | |
| SCHEMBL8333228 | 0.76 | SPHK1 (0.54) | SPHK1EPHX1CASP2NAAAHPGD | |
| SCHEMBL1237682 | 0.76 | HPGD (0.56) | SPHK1EPHX1CASP2NAAAHPGD | |
| SCHEMBL1236881 | 0.76 | HPGD (0.56) | SPHK1EPHX1CASP2NAAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834393-B2 | Organic compounds having taste-modifying properties | GIVAUDAN SA (CH) | 2023-12-05 | — | — | US | claimed |
| US-20210147345-A1 | Organic Compounds having Taste-Modifying Properties | GIVAUDAN SA (CH) | 2021-05-20 | — | — | US | claimed |
| CN-105592720-B | Organic compounds with taste-improving properties | 奇华顿股份有限公司 | 2020-07-07 | — | — | CN | claimed |
| EP-3057444-B1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | GIVAUDAN SA (CH) | 2017-12-06 | — | — | EP | claimed |
| EP-3057444-A1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | Givaudan SA (CH) | 2016-08-24 | — | — | EP | claimed |
| US-20160227825-A1 | Organic Compounds having Taste-Modifying Properties | GIVAUDAN SA (CH) | 2016-08-11 | — | — | US | claimed |
| CN-105592720-A | Organic compounds having taste-modifying properties | GIVAUDAN SA | 2016-05-18 | — | — | CN | claimed |
| WO-2015048991-A1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | GIVAUDAN SA (CH) | 2015-04-09 | — | — | WO | claimed |
| US-11834393-B2 | Organic compounds having taste-modifying properties | GIVAUDAN SA (CH) | 2023-12-05 | — | — | US | disclosed |
| US-20210147345-A1 | Organic Compounds having Taste-Modifying Properties | GIVAUDAN SA (CH) | 2021-05-20 | — | — | US | disclosed |
| CN-105592720-B | Organic compounds with taste-improving properties | 奇华顿股份有限公司 | 2020-07-07 | — | — | CN | disclosed |
| EP-3057444-B1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | GIVAUDAN SA (CH) | 2017-12-06 | — | — | EP | disclosed |
| EP-3057444-A1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | Givaudan SA (CH) | 2016-08-24 | — | — | EP | disclosed |
| US-20160227825-A1 | Organic Compounds having Taste-Modifying Properties | GIVAUDAN SA (CH) | 2016-08-11 | — | — | US | disclosed |
| CN-105592720-A | Organic compounds having taste-modifying properties | GIVAUDAN SA | 2016-05-18 | — | — | CN | disclosed |
| WO-2015048991-A1 | ORGANIC COMPOUNDS HAVING TASTE-MODIFYING PROPERTIES | GIVAUDAN SA (CH) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160227825-A1 | Organic Compounds having Taste-Modifying Properties | TAS2R5, TAS2R3, TAS2R1 | SPHK1 3730/4885EPHX1 4126/4885CASP2 1709/4885 |
| US-11834393-B2 | Organic compounds having taste-modifying properties | TAS2R5, TAS2R3, TAS2R1 | SPHK1 3730/4885EPHX1 4126/4885CASP2 1709/4885 |
| US-20210147345-A1 | Organic Compounds having Taste-Modifying Properties | TAS2R5, TAS2R3, TAS2R1 | SPHK1 3730/4885EPHX1 4126/4885CASP2 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.