Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL2729573 | 0.83 | TSHR (0.70) | TSHRDAONAPRTSRD5A2CES2 | |
| SCHEMBL6139393 | 0.81 | RNPEP (0.37) | ALDH1A1TP53 | |
| Benzoic Acid SCHEMBL1784575 | 0.79 | TSHR (0.48) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL1784214 | 0.79 | TSHR (0.48) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL5147655 | 0.79 | DAO (0.48) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL1783909 | 0.78 | TSHR (0.47) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL4578701 | 0.77 | TSHR (0.50) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL574292 | 0.77 | DAO (0.45) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL26630639 | 0.77 | DAO (0.45) | TSHRDAONAPRTSRD5A2CES2 | |
| Benzoic Acid SCHEMBL1787177 | 0.76 | TSHR (0.48) | TSHRDAONAPRTSRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050685-A1 | BENZOATE BLEND | FERRO CORPORATION (US) | 2015-04-09 | — | — | WO | claimed |
| WO-2015050685-A1 | BENZOATE BLEND | FERRO CORPORATION (US) | 2015-04-09 | — | — | WO | disclosed |