Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | CES2 | O00748 | 4/20 | 0.58 |
| ▸ | CES1 | P23141 | 4/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL20676742 | 0.90 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28327607 | 0.90 | TSHR (0.78) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7436169 | 0.88 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28229104 | 0.88 | TSHR (0.67) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL5607281 | 0.87 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7865148 | 0.87 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1913806 | 0.87 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL20450033 | 0.87 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL15658034 | 0.86 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzil SCHEMBL11293167 | 0.85 | CES2 (0.70) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118660812-A | Interlayer with light reflector and laminated glass | 首诺公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-118647505-A | Interlayer with light reflector and laminated glass | 首诺公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118284509-A | Polymer interlayers having reduced edge blisters | 首诺公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-111201134-B | Poly (vinyl acetal) resin composition, layer and interlayer having enhanced properties | 首诺公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-110050042-A | Suitable for shifting the composition of (LIFT) application forward using induced with laser | 汉高股份有限及两合公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-107207636-B | Adhesive composition for hard-gloss paint | 巴斯夫欧洲公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109071994-A | The product for being subjected to ice formation including the rejection surface comprising fluorochemical materials | 3M创新有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105189563-B | The technique for producing high solid starch dispersion liquid using multistage edman degradation Edman | 盛禧奥欧洲有限公司 | 2018-09-11 | — | — | CN | disclosed |
| CN-104334661-B | pavement marking composition | 3M创新有限公司 | 2018-04-06 | — | — | CN | disclosed |
| US-20180029340-A1 | MULTIPLE LAYER INTERLAYER HAVING IMPROVED OPTICAL AND SOUND INSULATION PROPERTIES | SOLUTIA INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-20160159050-A1 | MULTIPLE LAYER INTERLAYER HAVING IMPROVED OPTICAL AND SOUND INSULATION PROPERTIES | SOLUTIA INC. (US) | 2016-06-09 | — | — | US | disclosed |
| EP-2632965-A1 | AQUEOUS CATIONIC POLYURETHANE DISPERSIONS | Lubrizol Advanced Materials, Inc. (US) | 2013-09-04 | — | — | EP | disclosed |
| CN-101184530-B | Breathable polyurethanes, blends, and articles | LUBRIZOL ADVANCED MAT INC | 2012-07-04 | — | — | CN | disclosed |
| WO-2012058534-A1 | AQUEOUS CATIONIC POLYURETHANE DISPERSIONS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2012-05-03 | — | — | WO | disclosed |
| CN-101184530-A | Breathable polyurethanes, blends, and articles | LUBRIZOL ADVANCED MAT INC (US) | 2008-05-21 | — | — | CN | disclosed |
| EP-1301564-A1 | PLASTICIZED WATERBORNE POLYURETHANE DISPERSIONS AND MANUFACTURING PROCESS | Noveon IP Holdings Corp. (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002008327-A1 | PLASTICIZED WATERBORNE POLYURETHANE DISPERSIONS AND MANUFACTURING PROCESS | NOVEON IP HOLDINGS CORP. (US) | 2002-01-31 | — | — | WO | disclosed |
| US-4273820-A | FOAMED PLASTIC AND HEAT CURED TRANSLUCENT LAYERS | GAF CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |
| US-4124707-A | 7α-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor | SCHERING CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4022943-A | CURING POYVINYL CHLORIDE ANDOR POLYURETHANE | GAF CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |