Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30435358 | 0.85 | TSHR (0.38) | TSHRPOLBSNCAALDH1A1GPR35 | |
| SCHEMBL25272699 | 0.83 | GRIA2 (0.31) | CYP1A2 | |
| SCHEMBL28623192 | 0.79 | TSHR (0.49) | TSHRPOLBCYP1A2CHEK1SNCA | |
| SCHEMBL30208637 | 0.79 | TSHR (0.49) | TSHRPOLBCYP1A2CHEK1SNCA | |
| SCHEMBL25259135 | 0.78 | — | — | |
| SCHEMBL14270203 | 0.77 | MAPT (0.44) | TSHRSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL4978604 | 0.77 | TSHR (0.46) | TSHRPOLBCYP1A2CHEK1SNCA | |
| SCHEMBL5284482 | 0.77 | TSHR (0.46) | TSHRPOLBCYP1A2CHEK1SNCA | |
| SCHEMBL13576811 | 0.76 | MAPT (0.42) | TSHRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL14270204 | 0.75 | TTR (0.45) | SMN1; SMN2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180237-A1 | METHOD AND COMPOUND | ATDBio Limited (GB) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023099471-A1 | METHOD FOR PRODUCING POLYNUCLEOTIDES | ATDBio Limited (GB) | 2023-06-08 | — | — | WO | disclosed |
| EP-3052653-A1 | A METHOD OF IDENTIFYING OR PRODUCING AN APTAMER | Tolle, Fabian (DE) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015049356-A1 | A METHOD OF IDENTIFYING OR PRODUCING AN APTAMER | TOLLE FABIAN (DE) | 2015-04-09 | — | — | WO | disclosed |