Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437048 | 0.89 | TSHR (0.47) | TSHRLOXL2SNCAALDH1A1POLB | |
| SCHEMBL13284231 | 0.87 | LOXL2 (0.47) | TSHRLOXL2SNCAALDH1A1POLB | |
| SCHEMBL30208637 | 0.87 | TSHR (0.49) | TSHRSNCAALDH1A1POLBCYP1A2 | |
| SCHEMBL28623192 | 0.87 | TSHR (0.49) | TSHRSNCAALDH1A1POLBCYP1A2 | |
| SCHEMBL10524423 | 0.84 | LOXL2 (0.52) | TSHRLOXL2SNCAALDH1A1POLB | |
| SCHEMBL5284482 | 0.84 | TSHR (0.46) | TSHRSNCAALDH1A1POLBCYP1A2 | |
| SCHEMBL9815417 | 0.80 | TSHR (0.55) | TSHRSNCAALDH1A1POLBCYP1A2 | |
| SCHEMBL9477777 | 0.78 | BACE1 (0.47) | TSHRSNCAALDH1A1CYP1A2GPR35 | |
| SCHEMBL5983177 | 0.77 | TSHR (0.46) | TSHRSNCAALDH1A1POLBCYP1A2 | |
| SCHEMBL5284406 | 0.77 | MAPT (0.41) | TSHRALDH1A1CYP1A2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018218250-A2 | PHOTOACTIVE COMPOUNDS AND METHODS FOR BIOMOLECULE DETECTION AND SEQUENCING | VIBRANT HOLDINGS, LLC (US) | 2018-11-29 | — | — | WO | disclosed |
| WO-2015054050-A1 | PROBING OF BIOLOGICAL SAMPLES | GENERAL ELECTRIC COMPANY (US) | 2015-04-16 | — | — | WO | disclosed |
| EP-1730307-A4 | PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES FOR DNA SEQUENCING ON CHIP CONSTRUCTED BY SITE-SPECIFIC COUPLING CHEMISTRY | UNIV COLUMBIA (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1730307-A2 | PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES FOR DNA SEQUENCING ON CHIP CONSTRUCTED BY SITE-SPECIFIC COUPLING CHEMISTRY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005084367-A2 | PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES FOR DNA SEQUENCING ON CHIP CONSTRUCTED BY SITE-SPECIFIC COUPLING CHEMISTRY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-09-15 | — | — | WO | disclosed |