Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17204225 | 0.88 | KDM4E (0.39) | SLC2A1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL4365069 | 0.82 | CTNNB1 (0.47) | SLC2A1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL263154 | 0.80 | SLC2A1 (0.74) | SLC2A1SMN1; SMN2PARP1IP6K1IP6K3 | |
| SCHEMBL27673206 | 0.78 | KDM4E (0.47) | SLC2A1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL4365079 | 0.76 | CTNNB1 (0.47) | SLC2A1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL30729983 | 0.75 | TDP1 (0.41) | KDM4ERAB9AALDH1A1HPGDHTT | |
| SCHEMBL25021728 | 0.74 | PARP1 (0.60) | ALDH1A1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL12182684 | 0.74 | PARP1 (0.60) | SLC2A1KDM4ESMN1; SMN2PARP1IP6K1 | |
| Acetic Acid SCHEMBL10727228 | 0.74 | SMN1; SMN2 (0.49) | SLC2A1KDM4ERAB9AALDH1A1HPGD | |
| SCHEMBL5505380 | 0.74 | IP6K1 (0.44) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | claimed |
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |