Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 6/20 | 0.44 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.44 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 6/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197466 | 0.79 | IP6K1 (0.68) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL30434581 | 0.79 | IP6K1 (0.68) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| SCHEMBL25021728 | 0.76 | PARP1 (0.60) | PARP1CHEK1PIM1AKT1FLT3 | |
| SCHEMBL12182684 | 0.76 | PARP1 (0.60) | IP6K1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL5790916 | 0.76 | PARP1 (0.60) | IP6K1PARP1CHEK1PIM1AKT1 | |
| SCHEMBL16618906 | 0.74 | SLC2A1 (0.49) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| Formic Acid SCHEMBL10727380 | 0.73 | PDPK1 (0.50) | IP6K1IP6K3IP6K2PARP1KDM4E | |
| SCHEMBL1418704 | 0.73 | HDAC1 (0.56) | KDM4EKMT2AALDH1A1POLBP2RY14 | |
| SCHEMBL4365076 | 0.73 | IP6K1 (0.38) | IP6K1IP6K3IP6K2PARP1CHEK1 | |
| Formic Acid SCHEMBL10738924 | 0.72 | PDPK1 (0.49) | IP6K1IP6K3IP6K2PARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845988-A2 | SUBSTITUTED IMIDAZOQUINOLINES AND IMIDAZONAPHTHYRIDINES | 3M Innovative Properties Company (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006091394-A2 | SUBSTITUTED IMIDAZOQUINOLINES AND IMIDAZONAPHTHYRIDINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |