Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12936323 | 0.88 | HTT (0.41) | KMT2AMEN1L3MBTL1MAPTTDP1 | |
| SCHEMBL16619494 | 0.84 | MAPT (0.42) | KMT2AMEN1L3MBTL1MAPTTDP1 | |
| SCHEMBL4033049 | 0.82 | MAPT (0.54) | KMT2AMEN1MAPTTDP1VCAM1 | |
| SCHEMBL7401817 | 0.81 | HTT (0.54) | KMT2AMEN1L3MBTL1MAPTTDP1 | |
| SCHEMBL29171380 | 0.80 | HTT (0.57) | KMT2AMEN1L3MBTL1MAPTTDP1 | |
| SCHEMBL8322081 | 0.80 | KMT2A (0.43) | KMT2AMEN1L3MBTL1MAPTTDP1 | |
| SCHEMBL2911094 | 0.80 | KMT2A (0.58) | KMT2AMEN1L3MBTL1MAPTTDP1 | |
| SCHEMBL28342808 | 0.79 | ERN1 (0.49) | KMT2AMEN1MAPTTDP1VCAM1 | |
| SCHEMBL22117910 | 0.78 | S1PR4 (0.44) | KMT2AMEN1L3MBTL1MAPTTDP1 | |
| SCHEMBL31174878 | 0.78 | S1PR4 (0.44) | KMT2AMEN1L3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |