Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619045 | 0.84 | KMT2A (0.41) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL4468352 | 0.82 | MAPT (0.49) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL13140933 | 0.81 | MAPT (0.51) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL22117910 | 0.81 | S1PR4 (0.44) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL31174878 | 0.81 | S1PR4 (0.44) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL8110099 | 0.80 | TSHR (0.58) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL1610511 | 0.80 | SNCA (0.47) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL31415500 | 0.78 | S1PR4 (0.48) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL8322081 | 0.76 | KMT2A (0.43) | MAPTGAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL11100451 | 0.76 | KCNH2 (0.56) | MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |