Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | PPIG | Q13427 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631411 | 0.85 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL18982801 | 0.85 | TKT (0.39) | ALDH1A1GAACYP1A2LMNASMN1; SMN2 | |
| SCHEMBL2130827 | 0.85 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL14542484 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL22124308 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL432804 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL3502904 | 0.82 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL12426803 | 0.81 | GAA (0.53) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL4363215 | 0.81 | CYP4F2 (0.49) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| Hydrochloric Acid SCHEMBL6982968 | 0.81 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |